【学习及工作经历】

1978.10-1982.6 大连理工大学化学工程系学习（本科）

1983.9-1986.6 大连理工大学研究生院精细化工系学习（硕士研究生）

1986.7－1993.3 山东省化工研究院工作，工程师

1994.10－1998.3 日本名古屋大学，博士研究生，获得应用化学专业工学博士学位

1998.3－1999.9 山东大学化学院有机化学研究所，副教授

1999.10－2000.6 德国柏林工业大学有机化学研究所博士后研究员

2000.7－今 山东大学化学与化工学院有机化学研究所，教授

2003.7-2004.6 韩国昌原大学合成化学研究所博士后研究员

【主讲课程】

有机化学 （化学基地班，双语教学）

有机化学实验,

综合化学实验

有机合成新方法（研究生学位必修课）

合成化学（研究生必修课）

【研究领域和兴趣】

有机合成 荧光探针　药物化学，杂环化学, 化学生物学

【主要论著】

2018年

1. Miao-Fei Huang, Li-Na Chen, Jun-Ya Ning, Wen-Li Wu, Xiao-Dong He, Jun-Ying Miao*, Bao-Xiang Zhao*，

A new lipid droplets-targeted fluorescence probe for specific detection of SO2 derivatives in living cells,

Sensors and Actuators B 261 (2018) 196–202.

2. Long-Long Xi, Xue-Fei Guo, Chen-Liang Wang, Wen-Li Wu, Miao-Fei Huang, Jun-Ying Miao*, Bao-Xiang Zhao*,

A near-infrared ratiometric fluorescent probe for rapid and selective detection of hypochlorous acid in aqueous solution and living cells,  

Sensors and Actuators B 255 (2018) 666–671.

3. Dong-Peng Li, Xian-Jing Han, Ze-Quan Yan, Yun Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,

A far-red ratiometric fluorescent probe for SO2 derivatives based on the ESIPT enhanced FRET platform with improved performance,  

Dyes and Pigments 151 (2018) 95–101.

4. Li-Jie Zhang Jun-Ya Ning, Jun-Ying Miao, Jin-Ting Liu*, Bao-Xiang Zhao*,

A new ratiometric fluorescent probe for detecting endogenous HClO in living cells,

New J. Chem., 2018, 42, 2989--2993.

2017

1. Dong-Peng Li,Zhao-Yang Wang,Hao Su,Jun-Ying Miao* and Bao-Xiang Zhao*

Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform

Chem. Commun.,2017, 53, 577-58.

2. Shi-Li Shen,Xuan Zhao,Xiao-Fan Zhang,Xuan-Li Liu,Hao Wang,Yi-Ying Dai,Jun-Ying Miao and Bao-Xiang Zhao*

A mitochondria-targeted ratiometric fluorescent probe for hypochlorite and its applications in bioimaging

J. Mater. Chem. B, 2017, 5,289-295.

3. Wen-Li Wu, Han-Lin Ma, Miao-Fei Huang,Jun-Ying Miao,Bao-Xiang Zhao*

Mitochondria-targeted ratiometric fluorescent probe based on FRET for bisulfite

Sensors and Actuators B 241 (2017) 239–244.

4. Yan-Ru Zhang, Ying Liu, Xiao Feng, Bao-Xiang Zhao*

Recent progress in the development of fluorescent probes for the detection of hypochlorous acid

Sensors and Actuators B 240 (2017) 18–36.

5. Wen-Li Wu, Xuan Zhao, Long-Long Xi, Miao-Fei Huang, Wen-Hui Zeng, Jun-Ying Miao*, Bao-Xiang Zhao*

A mitochond ria-targetedfl uorescence probe for ratiometric detection of endogenous hypochlorite in the living cells

Analytica Chimica Acta 950 (2017) 178-183.

6. Shi-Li Shen, Jun-Ya Ning, Xiao-Fan Zhang, Jun-Ying Miao, Bao-Xiang Zhao*

Through-bond energy transfer-based ratiometric fluorescent probe for the imaging of HOCl in living cells

Sensors and Actuators B 244 (2017) 907–91

7. Qiong Yuan, Zhi-Min Zhao, Yan-Ru Zhang, Le Su, Jun-Ying Miao, Bao-Xiang Zhao*

A lysosome-targeted ratiometric fluorescent probe for detection of hypochlorous acid in living cells

Sensors and Actuators B 247 (2017) 736–741.

8. Li-Jie Zhang, Zhao-Yang Wang, Jin-Ting Liu, Jun-Ying Miao, Bao-Xiang Zhao*,  

A rational design of ratiometric fluorescent probes based on new ICT/FRET platform and imaging of endogenous sulfite in living cells，

Sensors and Actuators B 253 (2017) 19–26.

9. Dong-Peng Li, Zhao-Yang Wang, Jie Cui, Xin Wang, Jun-Ying Miao，Bao-Xiang Zhao*，

A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells，

Scientific RepoRts, 7:45294.

2016

1. Dong-Peng Li, Zhao-Yang Wang, Xiang-Jian Cao, Jie Cui, Xin Wang, Hao-Zhong Cui, Jun-Ying Miao*, Bao-Xiang Zhao*,

A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells,

Chem. Commun., 52 (2016) 2760--2763.

2. Xiao Feng, Tao Zhang, Jin-Ting Liu, Jun-Ying Miao*, Bao-Xiang Zhao*,

A new ratiometric fluorescent probe for rapid, sensitive and selective detection of endogenous hydrogen sulfide in mitochondria,

Chem. Commun. 52 (2016) 3131--3134.

3. Wen-Li Wu,Zhao-Yang Wang, Xi Dai, Jun-Ying Miao & Bao-Xiang Zhao*，

An effective colorimetric and ratiometric fluorescent probe based FRET with a large Stokes shift for bisulfite.

Scientific Reports,6:25315 (2016).

4. Yan-Ru Zhang, Zhi-Min Zhao, Jun-Ying Miao, Bao-Xiang Zhao*,

A ratiometric fluorescence probe based on a novel FRET platform for imaging endogenous HOCl in the living cells,

Sensors and Actuators B 229 (2016) 408–413.

5. Xi Dai, Tao Zhang, Jun-Ying Miao*, Bao-Xiang Zhao*,

A ratiometric fluorescent probe with DNBS group for biothiols in aqueous solution,

Sensors and Actuators B 223 (2016) 274-279.

6. Xi  Dai, Zhao-Yang Wang, Zhi-Fang Du,Jun-Ying Miao,Bao-Xiang Zhao*,

A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging,

Sensors and Actuators B 232 (2016) 369–374.

7. Wen-Li Wu, Zhi-Min Zhao,Xi Dai, Le Su, Bao-Xiang Zhao,

A fast-response colorimetric and fluorescent probe for hypochlorite and its real applications in biological imaging

Sensors and Actuators B 232 (2016) 390–395

8. Jie  Cui, Tao Zhang, Yi-Qing Sun, Dong-Peng Li, Jin-Ting Liu, Bao-Xiang Zhao,

A highly sensitive and selective fluorescent probe for H2S detection with large fluorescence enhancement

Sensors and Actuators B 232 (2016) 705–711,

9. Dong-Peng Li, Jin-Feng Zhang, Jie Cui, Xiao-Feng Ma,  Jin-Ting Liu, Jun-Ying Miao,Bao-Xiang Zhao

A ratiometric fluorescent probe for fast detection of hydrogen sulfide and recognition of biological thiols

Sensors and Actuators B 234 (2016) 231–238

10. Li-Jie  Zhang, Zhao-Yang Wang, Xiang-Jian Cao, Jin-Ting Liu, Bao-Xiang Zhao,

An effective ICT-based and ratiometric fluorescent probe for sensing sulfite

Sensors and Actuators B 236 (2016) 741–748

11. Xiang-Jian Cao, Li-Na Chen, Xuan Zhang, Jin-Ting Liu, Ming-Yu Chen,Qiu-Rong Wu, Jun-Ying Miao*, Bao-Xiang Zhao*,

A NBD-based simple but effective fluorescent pH probe for imaging of lysosomes in living cells，

Analytica Chimica Acta