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Paul Teesdale-Spittle PaulTeesdale-Spittle,ProfessorofVictoriaUniversityofWellington,LowerHutt,NewZealand.Hisresearchisprimarilyfocusedonthedesign,synthesisandevaluationofcompoundsforthetreatmentofcancerandparasiteinfection.Tothisend,hemakeuseofcomputationaltechniques(includingmolecularmodellingofligand-targetinteractionsandstructureactivityrelationshipanalysis),chemicalsynthesis(bysolutionandsolidphasetechniques,includingparallelcombinatorialsynthesis),andinvitroassays.CurrentprojectsinvolveinhibitorsofglutathioneS-transferaseenzymesasantiparasiticagents,pelorusideanditsanaloguesandbioreducibleanthraquinoneN-oxidetopoisomeraseinhibitorsasanticanceragents.HeisalsointerestedinunderstandingandharnessingWWdomains,whichareassociatedwithproteinrecognitionandbinding.
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